FMO2 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:2327, FMO1B1, FMO2, HGNC:3770, MIM:603955, NM_001301347, NM_001365900, NM_001460, NP_001288276, NP_001352829, NP_001451, NR_160266, XR_001737072, XR_921761, flavin containing dimethylaniline monoxygenase 2

Omim:OMIM:603955

Id:ENSG00000094963

Hgnc:HGNC:3770

Entrez:2327

Ensembl:ENSG00000094963

Description:flavin containing dimethylaniline monoxygenase 2

This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FMO2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with FMO2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FMO2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FMO2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FMO2.

Results found

Linked to

	Label	Description
	GSE226249 pirfenidone HL 0 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE163862 2 V 3 CISPLATIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE192750 adipose overexpression Grunt Fin PNMR OE 1 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE149880 2 V 1 TAMOXIFEN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE241036 0 V 1 ETHANOL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	T62-Spleen Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE164521 0 V 1 NITRIC OXIDE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE241036 0 V 3 ETHANOL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE189035 inositol 2 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE226249 pirfenidone HL 0 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE163862 2 V 3 CISPLATIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE192750 adipose overexpression Grunt Fin PNMR OE 1 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE149880 2 V 1 TAMOXIFEN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE241036 0 V 1 ETHANOL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE119007 prostaglandin TS-A clone E2 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

T62-Spleen Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE164521 0 V 1 NITRIC OXIDE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE241036 0 V 3 ETHANOL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE189035 inositol 2 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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