GRWD1 (Gene)

Organism:

Homo sapiens

Synonyms:CDW4, ENTREZ:83743, GRWD, GRWD1, HGNC:21270, MIM:610597, NM_031485, NP_113673, RRB1, WDR28, glutamate rich WD repeat containing 1

Omim:OMIM:610597

Id:ENSG00000105447

Hgnc:HGNC:21270

Entrez:83743

Ensembl:ENSG00000105447

Description:glutamate rich WD repeat containing 1

This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GRWD1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GRWD1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GRWD1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GRWD1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GRWD1.

Results found

Linked to

	Label	Description
	GSE158834 ADIPOR2 knockout HEK293 7 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 etoposide leukocyte 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE151412 sorafenib 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE153871 cytarabine U2OS 4 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 7 V 3 PALMITIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE190937 AHCY MAT2A knockout Rael 4 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE193993 SSTR2 knockout 0 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE158834 ADIPOR2 knockout HEK293 7 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 etoposide leukocyte 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE151412 sorafenib 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE153871 cytarabine U2OS 4 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158834 7 V 3 PALMITIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE190937 AHCY MAT2A knockout Rael 4 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE193993 SSTR2 knockout 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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