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GAPDHS (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:26330, GAPD2, GAPDH-2, GAPDHS, GAPDS, HEL-S-278, HGNC:24864, HSD-35, MIM:609169, NM_014364, NP_055179, glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Omim:OMIM:609169
Id:ENSG00000105679
Hgnc:HGNC:24864
Entrez:26330
Ensembl:ENSG00000105679
Description:glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GAPDHS's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GAPDHS.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GAPDHS.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GAPDHS.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GAPDHS.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE228727 2 V 1 DAPAGLIFLOZIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE234148 HDAC inhibition 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE189653,GSE203344 5 V 3 FLUOXETINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE186226 KD knockdown T24 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE165174,GSE165175 0 V 1 TRAMETINIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 trametinib NF1 10 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE179235 MEK NRAS inhibition 5 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 10 V 3 TRAMETINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE179235 MEK NRAS inhibition 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE218773 ABL2 knockdown Hep-G2 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE228727 2 V 1 DAPAGLIFLOZIN MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE234148 HDAC inhibition 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE189653,GSE203344 5 V 3 FLUOXETINE MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE186226 KD knockdown T24 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE165174,GSE165175 0 V 1 TRAMETINIB MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 10 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 5 v 6 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 10 V 3 TRAMETINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 4 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE218773 ABL2 knockdown Hep-G2 2 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.