Synonyms:ENTREZ:7704, HGNC:12930, MIM:176797, NM_001018011, NM_001354750, NM_001354751, NM_001354752, NM_006006, NP_001018011, NP_001341679, NP_001341680, NP_001341681, NP_005997, PLZF, XM_005271658, XM_017018259, XM_024448681, XP_005271715, XP_016873748, XP_024304449, XR_001747955, ZBTB16, ZNF145, zinc finger and BTB domain containing 16
Omim:OMIM:176797
Id:ENSG00000109906
Hgnc:HGNC:12930
Description:zinc finger and BTB domain containing 16
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]