PLA2G2D (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:26279, HGNC:9033, MIM:605630, NM_001271814, NM_012400, NP_001258743, NP_036532, PLA2G2D, PLA2IID, SPLASH, phospholipase A2 group IID, sPLA2-IID, sPLA2S

Omim:OMIM:605630

Id:ENSG00000117215

Hgnc:HGNC:9033

Entrez:26279

Ensembl:ENSG00000117215

Description:phospholipase A2 group IID

This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLA2G2D's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PLA2G2D.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLA2G2D.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLA2G2D.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLA2G2D.

Results found

Linked to

	Label	Description
	GSE193751 1 V 3 ORIDONIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE190178 MEK CDK8 inhibition 1 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE149901 3 V 0 ANLOTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 4 V 0 RUXOLITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	T66-Lung Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE128885 deferiprone macrophage 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 11 V 4 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE129811 5 V 0 NIACIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE193838 catechin 0 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	T67-Small-Intestine Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC

GSE193751 1 V 3 ORIDONIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE190178 MEK CDK8 inhibition 1 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE149901 3 V 0 ANLOTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 4 V 0 RUXOLITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

T66-Lung Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE128885 deferiprone macrophage 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 11 V 4 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE129811 5 V 0 NIACIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE193838 catechin 0 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

T67-Small-Intestine Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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