Synonyms:CD354, ENTREZ:54210, HGNC:17760, MIM:605085, NM_001242589, NM_001242590, NM_018643, NP_001229518, NP_001229519, NP_061113, NR_136332, TREM-1, TREM1, XM_006715117, XM_011514696, XM_011514697, XM_017010956, XM_017010957, XP_006715180, XP_011512998, XP_011512999, XP_016866445, XP_016866446, triggering receptor expressed on myeloid cells 1
Omim:OMIM:605085
Id:ENSG00000124731
Hgnc:HGNC:17760
Description:triggering receptor expressed on myeloid cells 1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]