Synonyms:ATG6, BECN1, ENTREZ:8678, HGNC:1034, MIM:604378, NM_001313998, NM_001313999, NM_001314000, NM_003766, NP_001300927, NP_001300928, NP_001300929, NP_003757, VPS30, XM_005257759, XM_005257760, XM_011525421, XM_017025262, XM_017025263, XM_017025264, XP_005257816, XP_005257817, XP_011523723, XP_016880751, XP_016880752, XP_016880753, beclin 1, beclin1
Omim:OMIM:604378
Id:ENSG00000126581
Hgnc:HGNC:1034
Description:beclin 1
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]