Synonyms:ENTREZ:6049, HGNC:10069, MIM:604242, NM_005977, NM_183043, NM_183044, NM_183045, NP_005968, NP_898864, NP_898865, NP_898866, RNF6, XM_005266485, XM_005266486, XM_011535177, XM_011535178, XM_017020685, XM_017020686, XM_017020687, XM_024449390, XM_024449391, XM_024449392, XP_005266542, XP_005266543, XP_011533479, XP_011533480, XP_016876174, XP_016876175, XP_016876176, XP_024305158, XP_024305159, XP_024305160, ring finger protein 6
Omim:OMIM:604242
Id:ENSG00000127870
Hgnc:HGNC:10069
Description:ring finger protein 6
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]