Synonyms:DPH2, DPH2L2, ENTREZ:1802, HGNC:3004, MIM:603456, NM_001039589, NM_001319165, NM_001319166, NM_001319167, NM_001319168, NM_001319169, NM_001319170, NM_001319171, NM_001384, NM_201399, NP_001034678, NP_001306094, NP_001306095, NP_001306096, NP_001306097, NP_001306098, NP_001306099, NP_001306100, NP_001375, XM_017000502, XP_016855991, diphthamide biosynthesis 2
Omim:OMIM:603456
Id:ENSG00000132768
Hgnc:HGNC:3004
Description:diphthamide biosynthesis 2
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]