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ELF5 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:E74 like ETS transcription factor 5, ELF5, ENTREZ:2001, ESE2, HGNC:3320, MIM:605169, NM_001243080, NM_001243081, NM_001422, NM_198381, NP_001230009, NP_001230010, NP_001413, NP_938195, XM_017017308, XM_017017309, XP_016872797, XP_016872798
Omim:OMIM:605169
Id:ENSG00000135374
Hgnc:HGNC:3320
Entrez:2001
Ensembl:ENSG00000135374
Description:E74 like ETS transcription factor 5
This gene encodes an epithelium-specific ETS family transcription factor. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. This gene has been implicated as a tumor suppressive transcription factor in breast cancer. [provided by RefSeq, May 2022]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ELF5's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ELF5.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ELF5.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ELF5.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ELF5.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE135514 8 V 7 DASATINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE111247 temozolomide LN-308 2 v 13 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE82032 trametinib HCC1143 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE109913 1 V 2 BLEOMYCIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216540 1 V 6 FULVESTRANT HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE115542 digoxin 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164529 0 V 2 TAMOXIFEN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164529 tamoxifen 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE135514 8 V 7 DASATINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE111247 temozolomide LN-308 2 v 13 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE82032 trametinib HCC1143 3 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE109913 1 V 2 BLEOMYCIN MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216540 1 V 6 FULVESTRANT HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115542 digoxin 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164529 0 V 2 TAMOXIFEN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164529 tamoxifen 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.