Synonyms:AGPAT10, AGPAT9, AYTL2, ENTREZ:79888, HGNC:25718, LPCAT-1, LPCAT1, MIM:610472, NM_024830, NP_079106, PFAAP3, XM_005248373, XM_011514132, XM_011514134, XM_017009879, XP_005248430, XP_011512434, XP_011512436, XP_016865368, lpcat, lysoPAFAT, lysophosphatidylcholine acyltransferase 1
Omim:OMIM:610472
Id:ENSG00000153395
Hgnc:HGNC:25718
Description:lysophosphatidylcholine acyltransferase 1
This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016]