Synonyms:ENTREZ:10600, HGNC:12614, MIM:604735, NM_001001992, NM_001032410, NM_006447, NP_001001992, NP_001027582, NP_006438, UBP-M, UBPM, USP16, XM_017028257, XM_017028258, XM_017028259, XM_017028260, XM_017028261, XM_024452045, XP_016883746, XP_016883747, XP_016883748, XP_016883749, XP_016883750, XP_024307813, ubiquitin specific peptidase 16
Omim:OMIM:604735
Id:ENSG00000156256
Hgnc:HGNC:12614
Description:ubiquitin specific peptidase 16
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]