HK3 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:3101, HGNC:4925, HK3, HKIII, HXK3, MIM:142570, NM_002115, NP_002106, XM_011534540, XM_017009411, XP_011532842, XP_016864900, XR_941101, XR_941102, hexokinase 3

Omim:OMIM:142570

Id:ENSG00000160883

Hgnc:HGNC:4925

Entrez:3101

Ensembl:ENSG00000160883

Description:hexokinase 3

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HK3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HK3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HK3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HK3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HK3.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE245968 FOXA1 inhibition Receptors Steroid Acetyltransferases 3 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE147662 3 V 5 NICOTINAMIDE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE191005 ENL knockout MOLM-13 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE201309 matrine 1 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE103510 STAT5 inhibition 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE110178 1 V 0 TRANYLCYPROMINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 crizotinib 6 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE150669 0 V 1 ROXADUSTAT MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE212231 GSE218491 SHP2 inhibition 3 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE245968 FOXA1 inhibition Receptors Steroid Acetyltransferases 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE147662 3 V 5 NICOTINAMIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE191005 ENL knockout MOLM-13 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE201309 matrine 1 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE103510 STAT5 inhibition 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE110178 1 V 0 TRANYLCYPROMINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE239844 crizotinib 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE150669 0 V 1 ROXADUSTAT MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE212231 GSE218491 SHP2 inhibition 3 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.