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LMX1A (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:DFNA7, ENTREZ:4009, HGNC:6653, LIM homeobox transcription factor 1 alpha, LMX1, LMX1.1, LMX1A, MIM:600298, NM_001033507, NM_001174069, NM_177398, NM_177399, NP_001167540, NP_796372, XM_011509538, XM_011509540, XP_011507840, XP_011507842
Omim:OMIM:600298
Id:ENSG00000162761
Hgnc:HGNC:6653
Entrez:4009
Ensembl:ENSG00000162761
Description:LIM homeobox transcription factor 1 alpha
This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LMX1A's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LMX1A.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LMX1A.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LMX1A.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LMX1A.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE210682 0 V 3 METHADONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE166536 3 V 2 DOCETAXEL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE189035 inositol 2 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE174498,GSE174500 5 V 8 ASPARAGINASE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE120792 BRCA1 inhibition Interferons 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE225901 dexamethasone 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE225901 2 V 1 DEXAMETHASONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119424 GSE120214 TBXT brachyury inhibition 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE129811 5 V 0 NIACIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE210682 0 V 3 METHADONE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE166536 3 V 2 DOCETAXEL MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE189035 inositol 2 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE174498,GSE174500 5 V 8 ASPARAGINASE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120792 BRCA1 inhibition Interferons 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE225901 dexamethasone 2 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE225901 2 V 1 DEXAMETHASONE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119424 GSE120214 TBXT brachyury inhibition 1 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE129811 5 V 0 NIACIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.