CXCL3 (Gene)

Organism:

Homo sapiens

Synonyms:C-X-C motif chemokine ligand 3, CINC-2b, CXCL3, ENTREZ:2921, GRO3, GROg, HGNC:4604, MIM:139111, MIP-2b, MIP2B, NM_002090, NP_002081, SCYB3

Omim:OMIM:139111

Id:ENSG00000163734

Hgnc:HGNC:4604

Entrez:2921

Ensembl:ENSG00000163734

Description:C-X-C motif chemokine ligand 3

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CXCL3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CXCL3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CXCL3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CXCL3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CXCL3.

Results found

Linked to

	Label	Description
	GSE218097 SOX10 overexpression glial cell 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE99875 everolimus 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE199859 A-7 HCA7 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 trehalose fibroblast 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE153867 olaparib 6 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE248770 STIM1 knockout Hep 3B2.1-7 Sorafenib 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE248770 sorafenib Hep 3B2.1-7 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE146612 amiodarone 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE128730 neratinib OVCAR-8 7 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE102505 tunicamycin 6 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE218097 SOX10 overexpression glial cell 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE99875 everolimus 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE199859 A-7 HCA7 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 trehalose fibroblast 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE153867 olaparib 6 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE248770 STIM1 knockout Hep 3B2.1-7 Sorafenib 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE248770 sorafenib Hep 3B2.1-7 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE146612 amiodarone 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE128730 neratinib OVCAR-8 7 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE102505 tunicamycin 6 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.