TKT (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:7086, HEL-S-48, HEL107, HGNC:11834, MIM:606781, NM_001064, NM_001135055, NM_001135056, NM_001258028, NP_001055, NP_001128527, NP_001244957, NR_047579, NR_047580, SDDHD, TK, TKT, TKT1, XM_011534054, XM_011534055, XP_011532356, XP_011532357, transketolase

Omim:OMIM:606781

Id:ENSG00000163931

Hgnc:HGNC:11834

Entrez:7086

Ensembl:ENSG00000163931

Description:transketolase

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TKT's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TKT.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TKT.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TKT.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TKT.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE120612 etoposide leukocyte 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214505 AKR1B1 knockdown A-549 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 digoxin 5 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE252944 AKT inhibition 7 v 9 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE151412 sorafenib 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE153871 cytarabine U2OS 4 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214505 AKR1B1 knockdown A-549 3 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE176008 pyridoxine 4 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE120612 etoposide leukocyte 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214505 AKR1B1 knockdown A-549 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 digoxin 5 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE252944 AKT inhibition 7 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE151412 sorafenib 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE153871 cytarabine U2OS 4 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214505 AKR1B1 knockdown A-549 3 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE176008 pyridoxine 4 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.