GGT6 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:124975, GGT6, HGNC:26891, MIM:612341, NM_001122890, NM_001288702, NM_001288703, NM_001288704, NM_153338, NP_001116362, NP_001275631, NP_001275632, NP_001275633, NP_699169, XM_024450572, XM_024450573, XP_024306340, XP_024306341, gamma-glutamyltransferase 6

Omim:OMIM:612341

Id:ENSG00000167741

Hgnc:HGNC:26891

Entrez:124975

Ensembl:ENSG00000167741

Description:gamma-glutamyltransferase 6

GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GGT6's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GGT6.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GGT6.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GGT6.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GGT6.

Results found

Linked to

	Label	Description
	GSE135514 8 V 7 DASATINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE158632 3 V 5 OXYQUINOLINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 11 V 9 CRIZOTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE168596 2 V 3 ADIPONECTIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE217552 fisetin 3 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE143782 calcitriol 3 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE217552 3 V 2 FISETIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE56010 adenosine 4 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE197571 FOXM1 RNF112 overexpression MGC-803 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE135514 8 V 7 DASATINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE158632 3 V 5 OXYQUINOLINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE239844 11 V 9 CRIZOTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE168596 2 V 3 ADIPONECTIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE217552 fisetin 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE143782 calcitriol 3 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE217552 3 V 2 FISETIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE56010 adenosine 4 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE197571 FOXM1 RNF112 overexpression MGC-803 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.