Synonyms:ENTREZ:8061, FOS like 1, AP-1 transcription factor subunit, FOSL1, FRA, FRA1, HGNC:13718, MIM:136515, NM_001300844, NM_001300855, NM_001300856, NM_001300857, NM_005438, NP_001287773, NP_001287784, NP_001287785, NP_001287786, NP_005429, NR_125339, fra-1
Omim:OMIM:136515
Id:ENSG00000175592
Hgnc:HGNC:13718
Description:FOS like 1, AP-1 transcription factor subunit
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]