SERPINB2 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:5055, HGNC:8584, HsT1201, MIM:173390, NM_001143818, NM_002575, NP_001137290, NP_002566, PAI, PAI-2, PAI2, PLANH2, SERPINB2, XM_024451192, XP_024306960, serpin family B member 2

Omim:OMIM:173390

Id:ENSG00000197632

Hgnc:HGNC:8584

Entrez:5055

Ensembl:ENSG00000197632

Description:serpin family B member 2

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SERPINB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SERPINB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SERPINB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SERPINB2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SERPINB2.

Results found

Linked to

	Label	Description
	GSE118548 trametinib T84 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE99875 everolimus 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 trametinib NF1 8 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE118548 1 V 2 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE119424 GSE120214 TBXT brachyury inhibition 7 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214306 CCM1 knockout 4 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE156648 DOT1L overexpression IMR-90 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE153867 olaparib 6 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE135514 dasatinib 8 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE236280 panobinostat 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE118548 trametinib T84 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE99875 everolimus 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 trametinib NF1 8 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE118548 1 V 2 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE119424 GSE120214 TBXT brachyury inhibition 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214306 CCM1 knockout 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE156648 DOT1L overexpression IMR-90 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE153867 olaparib 6 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE135514 dasatinib 8 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE236280 panobinostat 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.