LORICRIN (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:4014, HGNC:6663, LOR, LORICRIN, MIM:152445, NM_000427, NP_000418, XM_024447049, XP_024302817, loricrin cornified envelope precursor protein

Omim:OMIM:152445

Id:ENSG00000203782

Hgnc:HGNC:6663

Entrez:4014

Ensembl:ENSG00000203782

Description:loricrin cornified envelope precursor protein

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LORICRIN's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LORICRIN.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LORICRIN.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LORICRIN.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LORICRIN.

Results found

Linked to

	Label	Description
	GSE149880 2 V 1 TAMOXIFEN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE173483 nutlin-3 U2OS 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE213650 3 V 2 EVEROLIMUS HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE158431 2 V 6 PIOGLITAZONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE173577 MEK inhibition DK1 [Tursiops] 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE218580 1 V 4 FENTANYL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130956 2 V 1 ICARITIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE182150 KIT LSD1 MYC inhibition 2 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 0 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE149880 2 V 1 TAMOXIFEN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE173483 nutlin-3 U2OS 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE213650 3 V 2 EVEROLIMUS HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE158431 2 V 6 PIOGLITAZONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE173577 MEK inhibition DK1 [Tursiops] 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE218580 1 V 4 FENTANYL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130956 2 V 1 ICARITIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE182150 KIT LSD1 MYC inhibition 2 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 0 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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