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HSD3B2 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:3284, HGNC:5218, HSD3B, HSD3B2, HSDB, MIM:613890, NM_000198, NM_001166120, NP_000189, NP_001159592, SDR11E2, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Omim:OMIM:613890
Id:ENSG00000203859
Hgnc:HGNC:5218
Entrez:3284
Ensembl:ENSG00000203859
Description:hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HSD3B2's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HSD3B2.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HSD3B2.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HSD3B2.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HSD3B2.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE202434,GSE202438 2 V 14 TALAZOPARIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 4 v 14 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE159893 2 V 1 GENISTEIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

T64-Ovaries Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

GSE111247 temozolomide LN-308 11 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434,GSE202438 4 V 14 TALAZOPARIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE192870 2 V 0 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE236896 GSE237665 DNMT EZH2 inhibition 6 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE81796 enzalutamide LNCaP C4-2 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE202434,GSE202438 2 V 14 TALAZOPARIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 4 v 14 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE159893 2 V 1 GENISTEIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    T64-Ovaries Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    GSE111247 temozolomide LN-308 11 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434,GSE202438 4 V 14 TALAZOPARIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE192870 2 V 0 PALBOCICLIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE236896 GSE237665 DNMT EZH2 inhibition 6 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE81796 enzalutamide LNCaP C4-2 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.