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PRSS1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:5644, HGNC:9475, MIM:276000, NM_002769, NP_002760, PRSS1, TRP1, TRY1, TRY4, TRYP1, XM_011516411, XP_011514713, serine protease 1
Omim:OMIM:276000
Id:ENSG00000204983
Hgnc:HGNC:9475
Entrez:5644
Ensembl:ENSG00000204983
Description:serine protease 1
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRSS1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PRSS1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRSS1.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRSS1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRSS1.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE108464 AZ-628 11 v 12 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE236228 penfluridol 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE202434 GSE202438 talazoparib 4 v 14 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE244730 erlotinib PC-9 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE169617 azacitidine 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE85880 GSE85881 tretinoin cardiac muscle cell 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE114708 mitochondrial inhibition Monocarboxylic Acid Transporters 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE108464 AZ-628 11 v 12 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE236228 penfluridol 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE202434 GSE202438 talazoparib 4 v 14 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE244730 erlotinib PC-9 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE183741 GSE183806 POU2F2 POU2AF1 knockdown UtE-iPS-1 2 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE169617 azacitidine 1 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880 GSE85881 tretinoin cardiac muscle cell 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE114708 mitochondrial inhibition Monocarboxylic Acid Transporters 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.