SLC5A8 (Gene)

Organism:

Homo sapiens

Synonyms:AIT, ENTREZ:160728, HGNC:19119, MIM:608044, NM_145913, NP_666018, SLC5A8, SMCT, SMCT1, XM_017018910, XP_016874399, XR_944503, solute carrier family 5 member 8

Id:ENSG00000256870

Entrez:160728

Ensembl:ENSG00000256870

Description:solute carrier family 5 member 8

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SLC5A8's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SLC5A8.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SLC5A8.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SLC5A8.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SLC5A8.

Results found

Linked to

	Label	Description
	GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE139987 1 V 0 ROSIGLITAZONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE238116 EGR1 HCC overexpression MHCC97-H PLC-PRF-5 3 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE210655 1 V 0 CISPLATIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 9 V 3 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE207514,GSE207515 2 V 3 ACETYLCYSTEINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE185200 GSE185202 L-13 Ali-BL 0 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE157109 TRIM8 knockdown MCF-7 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135514 dasatinib 8 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE139987 1 V 0 ROSIGLITAZONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE238116 EGR1 HCC overexpression MHCC97-H PLC-PRF-5 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE210655 1 V 0 CISPLATIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 9 V 3 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE207514,GSE207515 2 V 3 ACETYLCYSTEINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE185200 GSE185202 L-13 Ali-BL 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE157109 TRIM8 knockdown MCF-7 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE135514 dasatinib 8 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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