H2AB2 (Gene)

Entrez:474381

Description:H2A.B variant histone 2

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy. [provided by RefSeq, Oct 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View H2AB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with H2AB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using H2AB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for H2AB2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with H2AB2.

Results found

Linked to

	Label	Description
	GSE200982 PLAC8 knockout 0 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 crizotinib 8 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 8 V 10 CRIZOTINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 trehalose fibroblast 7 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE184892 7 V 1 TREHALOSE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE231745 1 V 0 VENETOCLAX HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE100148 EZH2 inhibition 8 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE100148 EZH2 inhibition 9 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE103068 5 V 8 VOLASERTIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE128076 doxycycline HEK293 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE200982 PLAC8 knockout 0 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE239844 crizotinib 8 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE239844 8 V 10 CRIZOTINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 trehalose fibroblast 7 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE184892 7 V 1 TREHALOSE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE231745 1 V 0 VENETOCLAX HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE100148 EZH2 inhibition 8 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE100148 EZH2 inhibition 9 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE103068 5 V 8 VOLASERTIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE128076 doxycycline HEK293 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

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CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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