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4D Nucleome (4DN)

The goal of the Common Fund’s 4D Nucleome (4DN) program is to study the three-dimensional organization of the nucleus in space and time (the 4th dimension). The nucleus of a cell contains DNA, the genetic “blueprint” that encodes all of the genes a living organism uses to produce proteins needed to carry out life-sustaining cellular functions. Scientists know that how the information in the nucleus organized, stored, and unpackaged are all important to basic human health and we are only starting to learn how changes in this organization can lead to the development of different diseases, such as cancer or our response to infectious agents like viruses. (Retrieved from the NIH Common Fund site)

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    4DN.zip

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    Creator: 4DN

    Filesize: 49.2 Mb

    Date Modified: 5/8/2024

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    4DN.edges.csv

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    Filesize: 397.1 Mb

    Date Modified: 10/26/2023

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Landmark Publications

The 4D nucleome project.Dekker J et al. | Nature | Published: 2017
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