POLR2K (Gene)

Organism:

Homo sapiens

Synonyms:ABC10-alpha, ENTREZ:5440, HGNC:9198, MIM:606033, NM_005034, NP_005025, POLR2K, RNA polymerase II, I and III subunit K, RPABC4, RPB10alpha, RPB12, RPB7.0, hRPB7.0, hsRPB10a

Omim:OMIM:606033

Id:ENSG00000147669

Hgnc:HGNC:9198

Entrez:5440

Ensembl:ENSG00000147669

Description:RNA polymerase II, I and III subunit K

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View POLR2K's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with POLR2K.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using POLR2K.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for POLR2K.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POLR2K.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE158834 ADIPOR2 knockout HEK293 7 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 7 V 3 PALMITIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE142588 cinobufagin 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE168602 GSE168604 selumetinib COLO205 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193993 SSTR2 knockout 4 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE133927 PTEN p53 Meox1 knockdown BT-549 RNA Small Interfering 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE235587 mitoxantrone KYSE-70 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE190178 MEK CDK8 inhibition 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 trametinib NF1 10 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE158834 ADIPOR2 knockout HEK293 7 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158834 7 V 3 PALMITIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE142588 cinobufagin 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE168602 GSE168604 selumetinib COLO205 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193993 SSTR2 knockout 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE133927 PTEN p53 Meox1 knockdown BT-549 RNA Small Interfering 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE235587 mitoxantrone KYSE-70 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE190178 MEK CDK8 inhibition 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 trametinib NF1 10 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.