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NKX2-6 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CSX2, CTHM, ENTREZ:137814, HGNC:32940, MIM:611770, NK2 homeobox 6, NKX2-6, NKX2F, NKX4-2, NM_001136271, NP_001129743
Id:ENSG00000180053
Entrez:137814
Ensembl:ENSG00000180053
Description:NK2 homeobox 6
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NKX2-6's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NKX2-6.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NKX2-6.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NKX2-6.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NKX2-6.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE220806 1 V 3 PROGESTERONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE255432 7 V 3 IMEGLIMIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE168596 2 V 3 ADIPONECTIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE220806 progesterone fibroblast 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119424 GSE120214 TBXT brachyury inhibition 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE220806 0 V 3 PROGESTERONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119424 GSE120214 TBXT brachyury inhibition 5 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE160349 IDAM T cell 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE220806 1 V 3 PROGESTERONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE255432 7 V 3 IMEGLIMIN MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE168596 2 V 3 ADIPONECTIN MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE220806 progesterone fibroblast 0 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119424 GSE120214 TBXT brachyury inhibition 5 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE220806 0 V 3 PROGESTERONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119424 GSE120214 TBXT brachyury inhibition 5 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE160349 IDAM T cell 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.